Comparative KEGG Pathways:
Apicomplexan Parasites vs. Human
questions: fengchen@sas.upenn.edu
1. Metabolism
1.1 Carbohydrate Metabolism
Glycolysis / Gluconeogenesis
Gene Table
Citrate cycle (TCA cycle)
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Pentose phosphate pathway
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Pentose and glucuronate interconversions
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Fructose and mannose metabolism
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Galactose metabolism
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Ascorbate and aldarate metabolism
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Starch and sucrose metabolism
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Aminosugars metabolism
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Nucleotide sugars metabolism
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Pyruvate metabolism
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Glyoxylate and dicarboxylate metabolism
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Propanoate metabolism
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Butanoate metabolism
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C5-Branched dibasic acid metabolism
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Inositol metabolism
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Inositol phosphate metabolism
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1.2 Energy Metabolism
Oxidative phosphorylation
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ATP synthesis
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Photosynthesis
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Carbon fixation
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Reductive carboxylate cycle (CO2 fixation)
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Methane metabolism
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Nitrogen metabolism
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Sulfur metabolism
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1.3 Lipid Metabolism
Fatty acid biosynthesis (path 1)
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Fatty acid biosynthesis (path 2)
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Fatty acid metabolism
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Synthesis and degradation of ketone bodies
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Biosynthesis of steroids
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Bile acid biosynthesis
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C21-Steroid hormone metabolism
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Androgen and estrogen metabolism
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Glycerolipid metabolism
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Phospholipid degradation
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Prostaglandin and leukotriene metabolism
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1.4 Nucleotide Metabolism
Purine metabolism
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Pyrimidine metabolism
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1.5 Amino Acid Metabolism
Glutamate metabolism
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Alanine and aspartate metabolism
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Glycine, serine and threonine metabolism
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Methionine metabolism
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Cysteine metabolism
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Valine, leucine and isoleucine degradation
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Valine, leucine and isoleucine biosynthesis
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Lysine biosynthesis
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Lysine degradation
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Arginine and proline metabolism
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Histidine metabolism
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Tyrosine metabolism
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Phenylalanine metabolism
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Tryptophan metabolism
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Phenylalanine, tyrosine and tryptophan biosynthesis
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Urea cycle and metabolism of amino groups
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1.6 Metabolism of Other Amino Acids
beta-Alanine metabolism
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Taurine and hypotaurine metabolism
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Aminophosphonate metabolism
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Selenoamino acid metabolism
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Cyanoamino acid metabolism
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D-Glutamine and D-glutamate metabolism
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D-Arginine and D-ornithine metabolism
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D-Alanine metabolism
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Glutathione metabolism
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1.7 Glycan Biosynthesis and Metabolism
N-Glycan biosynthesis
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High-mannose type N-glycan biosynthesis
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N-Glycan degradation
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O-Glycan biosynthesis
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Chondroitin / heparan sulfate biosynthesis
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Keratan sulfate biosynthesis
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Glycosaminoglycan degradation
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Lipopolysaccharide biosynthesis
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Peptidoglycan biosynthesis
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Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
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Glycosphingolipid metabolism
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Blood group glycolipid biosynthesis - lactoseries
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Blood group glycolipid biosynthesis - neo-lactoseries
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Globoside metabolism
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Ganglioside biosynthesis
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1.8 Biosynthesis of Polyketides and Nonribosomal Peptides
Type I polyketide structures
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Biosynthesis of 12-, 14- and 16-membered macrolides
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Biosynthesis of ansamycins
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Biosynthesis of type II polyketide backbone
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Biosynthesis of type II polyketide products
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Polyketide sugar unit biosynthesis
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Nonribosomal peptide structures
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Biosynthesis of siderophore group nonribosomal peptides
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Biosynthesis of vancomycin group antibiotics
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1.9 Metabolism of Cofactors and Vitamins
Thiamine metabolism
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Riboflavin metabolism
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Vitamin B6 metabolism
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Nicotinate and nicotinamide metabolism
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Pantothenate and CoA biosynthesis
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Biotin metabolism
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Folate biosynthesis
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One carbon pool by folate
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Retinol metabolism
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Porphyrin and chlorophyll metabolism
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Ubiquinone biosynthesis
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1.10 Biosynthesis of Secondary Metabolites
Terpenoid biosynthesis
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Diterpenoid biosynthesis
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Monoterpenoid biosynthesis
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Limonene and pinene degradation
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Indole and ipecac alkaloid biosynthesis
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Stilbene, coumarine and lignin biosynthesis
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Flavonoid biosynthesis
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Alkaloid biosynthesis I
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Alkaloid biosynthesis II
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Penicillins and cephalosporins biosynthesis
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beta-Lactam resistance
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Streptomycin biosynthesis
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Tetracycline biosynthesis
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Clavulanic acid biosynthesis
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Puromycin biosynthesis
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Novobiocin biosynthesis
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1.11 Biodegradation of Xenobiotics
Caprolactam degradation
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Biphenyl degradation
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Toluene and xylene degradation
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gamma-Hexachlorocyclohexane degradation
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3-Chloroacrylic acid degradation
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1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
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2,4-Dichlorobenzoate degradation
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1,2-Dichloroethane degradation
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Tetrachloroethene degradation
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Styrene degradation
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1,4-Dichlorobenzene degradation
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Nitrobenzene degradation
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Ethylbenzene degradation
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Fluorene degradation
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Carbazole degradation
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Benzoate degradation via CoA ligation
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Benzoate degradation via hydroxylation
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Atrazine degradation
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Adapted from KEGG database.